WNK4 Full-Length MS Protein Standard


Product Description:

Name WNK4 Full-Length MS Protein Standard
Cat# CPFL323269
Protein Nameputative protein kinase WNK4
SymbolWNK4
SynonymsPHA2B; PRKWNK4
AccessionNM_032387
Cytogenetic17q21-q22
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW134.6 kDa
Expression TrueORF CloneRC223269
DescriptionWNK4 Full-Length MS Protein Standard (NP_115763), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a member of the WNK family of serine-threonine protein kinases. The kinase is part of the tight junction complex in kidney cells, and regulates the balance between NaCl reabsorption and K(+) secretion. The kinase regulates the activities of several types of ion channels, cotransporters, and exchangers involved in electrolyte flux in epithelial cells. Mutations in this gene result in pseudohypoaldosteronism type IIB.

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