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PEMT Full-Length MS Protein Standard

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Product Description


NamePEMT Full-Length MS Protein Standard
Cat#CPFL323190
Protein Namephosphatidylethanolamine N-methyltransferase
SymbolPEMT
SynonymsPEAMT; PEMPT; PEMT2; PNMT
AccessionNM_007169
Cytogenetic17p11.2
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionPEMT Full-Length MS Protein Standard (NP_009100), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. Phosphatidylcholine (PC) is the most abundant mammalian phospholipid. This gene encodes an enzyme which converts phosphatidylethanolamine to phosphatidylcholine by sequential methylation in the liver. Another distinct synthetic pathway in nucleated cells converts intracellular choline to phosphatidylcholine by a three-step process. The protein isoforms encoded by this gene localize to the endoplasmic reticulum and mitochondria-associated membranes. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms.

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