AKR1D1 Full-Length MS Protein Standard


Product Description:

Name AKR1D1 Full-Length MS Protein Standard
Cat# CPFL323056
Protein Namealdo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)
SymbolAKR1D1
Synonyms3o5bred; CBAS2; SRD5B1
AccessionNM_005989
Cytogenetic7q32-q33
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW37.2 kDa
Expression TrueORF CloneRC223056
DescriptionAKR1D1 Full-Length MS Protein Standard (NP_005980), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The enzyme encoded by this gene is responsible for the catalysis of the 5-beta-reduction of bile acid intermediates and steroid hormones carrying a delta(4)-3-one structure. Deficiency of this enzyme may contribute to hepatic dysfunction. Three transcript variants encoding different isoforms have been found for this gene. Other variants may be present, but their full-length natures have not been determined yet.

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