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GPBP1 Full-Length MS Protein Standard

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Product Description


NameGPBP1 Full-Length MS Protein Standard
Cat#CPFL322826
Protein NameGC-rich promoter binding protein 1
SymbolGPBP1
SynonymsGPBP; SSH6; VASCULIN
AccessionNM_022913
Cytogenetic5q11.2
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionGPBP1 Full-Length MS Protein Standard (NP_075064), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene was originally isolated by subtractive hybridization of cDNAs expressed in atherosclerotic plaques with a thrombus, and was found to be expressed only in vascular smooth muscle cells. However, a shorter splice variant was found to be more ubiquitously expressed. This protein is suggested to play a role in the development of atherosclerosis. Studies in mice suggest that it may also function as a GC-rich promoter-specific trans-activating transcription factor. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.

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