DOCK8 Full-Length MS Protein Standard


Product Description:

Name DOCK8 Full-Length MS Protein Standard
Cat# CPFL322789
Protein Namededicator of cytokinesis 8
SymbolDOCK8
SynonymsHEL-205; MRD2; ZIR8
AccessionNM_203447
Cytogenetic9p24.3
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW238.3 kDa
Expression TrueORF CloneRC222789
DescriptionDOCK8 Full-Length MS Protein Standard (NP_982272), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a member of the DOCK180 family of guanine nucleotide exchange factors. Guanine nucleotide exchange factors interact with Rho GTPases and are components of intracellular signaling networks. Mutations in this gene result in the autosomal recessive form of the hyper-IgE syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.

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