CYP7B1 Full-Length MS Protein Standard


Product Description:

Name CYP7B1 Full-Length MS Protein Standard
Cat# CPFL322647
Protein Namecytochrome P450, family 7, subfamily B, polypeptide 1
SymbolCYP7B1
SynonymsCBAS3; CP7B; SPG5A
AccessionNM_004820
Cytogenetic8q21.3
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW58.1 kDa
Expression TrueORF CloneRC222647
DescriptionCYP7B1 Full-Length MS Protein Standard (NP_004811), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway of extrahepatic tissues, which converts cholesterol to bile acids. This enzyme likely plays a minor role in total bile acid synthesis, but may also be involved in the development of atherosclerosis, neurosteroid metabolism and sex hormone synthesis.

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