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USP16 Full-Length MS Protein Standard

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Product Description


NameUSP16 Full-Length MS Protein Standard
Cat#CPFL322609
Protein Nameubiquitin specific peptidase 16
SymbolUSP16
SynonymsUBP-M; UBPM
AccessionNM_006447
Cytogenetic21q22.11
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionUSP16 Full-Length MS Protein Standard (NP_006438), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a deubiquitinating enzyme that is phosphorylated at the onset of mitosis and then dephosphorylated at the metaphase/anaphase transition. It can deubiquitinate H2A, one of two major ubiquitinated proteins of chromatin, in vitro and a mutant form of the protein was shown to block cell division. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

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