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ANKS1B Full-Length MS Protein Standard

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Product Description


NameANKS1B Full-Length MS Protein Standard
Cat#CPFL322572
Protein Nameankyrin repeat and sterile alpha motif domain containing 1B
SymbolANKS1B
SynonymsAIDA; AIDA-1; ANKS2; cajalin-2; EB-1; EB1
AccessionNM_020140
Cytogenetic12q23.1
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionANKS1B Full-Length MS Protein Standard (NP_064525), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a multi-domain protein that is predominantly expressed in brain and testis. This protein interacts with amyloid beta protein precursor (AbetaPP) and may have a role in normal brain development, and in the pathogenesis of Alzheimers disease. Expression of this gene has been shown to be elevated in patients with pre-B cell acute lymphocytic leukemia associated with t(1;19) translocation. Alternatively spliced transcript variants encoding different isoforms (some with different subcellular localization, PMID:15004329) have been described for this gene.

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