CHTF8 Full-Length MS Protein Standard


Product Description:

Name CHTF8 Full-Length MS Protein Standard
Cat# CPFL322566
Protein NameCTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)
SymbolCHTF8
SynonymsCTF8; DERPC
AccessionNM_001039690
Cytogenetic16q22.1
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW13.1 kDa
Expression TrueORF CloneRC222566
DescriptionCHTF8 Full-Length MS Protein Standard (NP_001034779), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a short protein that forms part of the Ctf18 replication factor C (RFC) complex that occurs in both yeast and mammals. The heteroheptameric RFC complex plays a role in sister chromatid cohesion and may load the replication clamp PCNA (proliferating cell nuclear antigen) onto DNA during DNA replication and repair. This gene is ubiquitously expressed and has been shown to have reduced expression in renal and prostate tumors. Alternatively spliced transcript variants have been described. This gene has a pseudogene on chromosome X.

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