P3H1 Full-Length MS Protein Standard


Product Description:

Name P3H1 Full-Length MS Protein Standard
Cat# CPFL322535
SymbolP3H1
SynonymsGROS1; LEPRE1; OI8
AccessionNM_022356
Cytogenetic1p34.1
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW83.2 kDa
Expression TrueORF CloneRC222535
DescriptionLEPRE1 Full-Length MS Protein Standard (NP_071751), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes an enzyme that is a member of the collagen prolyl hydroxylase family. These enzymes are localized to the endoplasmic reticulum and their activity is required for proper collagen synthesis and assembly. Mutations in this gene are associated with osteogenesis imperfecta type VIII. Three alternatively spliced transcript variants encoding different isoforms have been described. Other variants may exist, but their biological validity has not been determined.

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