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PDX1 Full-Length MS Protein Standard

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Product Description


NamePDX1 Full-Length MS Protein Standard
Cat#CPFL322354
Protein Namepancreatic and duodenal homeobox 1
SymbolPDX1
SynonymsGSF; IDX-1; IPF1; IUF1; MODY4; PAGEN1; PDX-1; STF-1
AccessionNM_000209
Cytogenetic13q12.1
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionPDX1 Full-Length MS Protein Standard (NP_000200), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).

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