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TYR Full-Length MS Protein Standard

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Product Description


NameTYR Full-Length MS Protein Standard
Cat#CPFL321797
Protein Nametyrosine
SymbolTYR
SynonymsATN; CMM8; OCA1; OCA1A; OCAIA; SHEP3
AccessionNM_000372
Cytogenetic11q14.3
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionTYR Full-Length MS Protein Standard (NP_000363), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3 half of this gene.

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