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CPT1A Full-Length MS Protein Standard

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Product Description


NameCPT1A Full-Length MS Protein Standard
Cat#CPFL321740
Protein Namecarnitine palmitoyltransferase 1A (liver)
SymbolCPT1A
SynonymsCPT1; CPT1-L; L-CPT1
AccessionNM_001876
Cytogenetic11q13.2
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionCPT1A Full-Length MS Protein Standard (NP_001867), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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