CPT1A Full-Length MS Protein Standard


Product Description:

Name CPT1A Full-Length MS Protein Standard
Cat# CPFL321740
Protein Namecarnitine palmitoyltransferase 1A (liver)
SymbolCPT1A
SynonymsCPT1; CPT1-L; L-CPT1
AccessionNM_001876
Cytogenetic11q13.2
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW88.2 kDa
Expression TrueORF CloneRC221740
DescriptionCPT1A Full-Length MS Protein Standard (NP_001867), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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