NGF Full-Length MS Protein Standard


Product Description:

Name NGF Full-Length MS Protein Standard
Cat# CPFL321463
Protein Namenerve growth factor (beta polypeptide)
SymbolNGF
SynonymsBeta-NGF; HSAN5; NGFB
AccessionNM_002506
Cytogenetic1p13.1
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW24.9 kDa
Expression TrueORF CloneRC221463
DescriptionNGF Full-Length MS Protein Standard (NP_002497), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. This protein has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in this gene have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of this genes expression is associated with allergic rhinitis.

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