TIGIT Full-Length MS Protein Standard


Product Description:

Name TIGIT Full-Length MS Protein Standard
Cat# CPFL321447
Protein NameT cell immunoreceptor with Ig and ITIM domains
SymbolTIGIT
SynonymsVSIG9; VSTM3; WUCAM
AccessionNM_173799
Cytogenetic3q13.31
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW26.1 kDa
Expression TrueORF CloneRC221447
DescriptionTIGIT Full-Length MS Protein Standard (NP_776160), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses.

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