MIB1 Full-Length MS Protein Standard


Product Description:

Name MIB1 Full-Length MS Protein Standard
Cat# CPFL321377
Protein Namemindbomb E3 ubiquitin protein ligase 1
SymbolMIB1
SynonymsDIP-1; DIP1; LVNC7; MIB; ZZANK2; ZZZ6
AccessionNM_020774
Cytogenetic18q11.2
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW110 kDa
Expression TrueORF CloneRC221377
DescriptionMIB1 Full-Length MS Protein Standard (NP_065825), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a protein containing multiple ankyrin repeats and RING finger domains that functions as an E3 ubiquitin ligase. The encoded protein positively regulates Notch signaling by ubiquitinating the Notch receptors, thereby facilitating their endocytosis. This protein may also promote the ubiquitination and degradation of death-associated protein kinase 1 (DAPK1).

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