| Name | NXN Full-Length MS Protein Standard |
|---|---|
| Cat# | CPFL321343 |
| Protein Name | nucleoredoxin |
| Symbol | NXN |
| Synonyms | NRX; TRG-4 |
| Accession | NM_022463 |
| Cytogenetic | 17p13.3 |
| Amino Acid Labeled | [U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys |
| Chemical Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Expression Host | Human HEK293 cells |
| Predicted MW | 48.2 kDa |
| Expression TrueORF Clone | RC221343 |
| Description | NXN Full-Length MS Protein Standard (NP_071908), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. Functions as a redox-dependent negative regulator of the Wnt signaling pathway, possibly by preventing ubiquitination of DVL3 by the BCR(KLHL12) complex. May also function as a transcriptional regulator act as a regulator of protein phosphatase 2A (PP2A). |
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