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TNFAIP3 Full-Length MS Protein Standard

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Product Description


NameTNFAIP3 Full-Length MS Protein Standard
Cat#CPFL321337
Protein Nametumor necrosis factor, alpha-induced protein 3
SymbolTNFAIP3
SynonymsA20; OTUD7C; TNFA1P2
AccessionNM_006290
Cytogenetic6q23
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionTNFAIP3 Full-Length MS Protein Standard (NP_006281), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). The protein encoded by this gene is a zinc finger protein and ubiqitin-editing enzyme, and has been shown to inhibit NF-kappa B activation as well as TNF-mediated apoptosis. The encoded protein, which has both ubiquitin ligase and deubiquitinase activities, is involved in the cytokine-mediated immune and inflammatory responses. Several transcript variants encoding the same protein have been found for this gene.

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