TPH1 Full-Length MS Protein Standard


Product Description:

Name TPH1 Full-Length MS Protein Standard
Cat# CPFL321254
Protein Nametryptophan hydroxylase 1
SymbolTPH1
SynonymsTPRH; TRPH
AccessionNM_004179
Cytogenetic11p15.3-p14
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW50.8 kDa
Expression TrueORF CloneRC221254
DescriptionTPH1 Full-Length MS Protein Standard (NP_004170), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger-related traits, bipolar disorder, suicidal behavior, addictions, and others.

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