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CYP11B1 Full-Length MS Protein Standard

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Product Description


NameCYP11B1 Full-Length MS Protein Standard
Cat#CPFL321240
Protein Namecytochrome P450, family 11, subfamily B, polypeptide 1
SymbolCYP11B1
SynonymsCPN1; CYP11B; FHI; P450C11
AccessionNM_001026213
Cytogenetic8q21
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionCYP11B1 Full-Length MS Protein Standard (NP_001021384), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and is involved in the conversion of progesterone to cortisol in the adrenal cortex. Mutations in this gene cause congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency. Transcript variants encoding different isoforms have been noted for this gene.

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