CRLF2 Full-Length MS Protein Standard


Product Description:

Name CRLF2 Full-Length MS Protein Standard
Cat# CPFL321190
Protein Namecytokine receptor-like factor 2
SymbolCRLF2
SynonymsCRL2; CRLF2Y; TSLPR
AccessionNM_022148
CytogeneticXp22.3; Yp11.3
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW41.8 kDa
Expression TrueORF CloneRC221190
DescriptionCRLF2 Full-Length MS Protein Standard (NP_071431), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene is a receptor for thymic stromal lymphopoietin (TSLP). Together with the interleukin 7 receptor (IL7R), the encoded protein and TSLP activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system. Two transcript variants encoding different isoforms have been found for this gene.

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