| Name | CRLF2 Full-Length MS Protein Standard |
|---|---|
| Cat# | CPFL321190 |
| Protein Name | cytokine receptor-like factor 2 |
| Symbol | CRLF2 |
| Synonyms | CRL2; CRLF2Y; TSLPR |
| Accession | NM_022148 |
| Cytogenetic | Xp22.3; Yp11.3 |
| Amino Acid Labeled | [U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys |
| Chemical Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Expression Host | Human HEK293 cells |
| Predicted MW | 41.8 kDa |
| Expression TrueORF Clone | RC221190 |
| Description | CRLF2 Full-Length MS Protein Standard (NP_071431), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene is a receptor for thymic stromal lymphopoietin (TSLP). Together with the interleukin 7 receptor (IL7R), the encoded protein and TSLP activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system. Two transcript variants encoding different isoforms have been found for this gene. |
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