GUCA2B Full-Length MS Protein Standard


Product Description:

Name GUCA2B Full-Length MS Protein Standard
Cat# CPFL321085
Protein Nameguanylate cyclase activator 2B (uroguanylin)
SymbolGUCA2B
SynonymsGCAP-II; UGN
AccessionNM_007102
Cytogenetic1p34-p33
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW11.9 kDa
Expression TrueORF CloneRC221085
DescriptionGUCA2B Full-Length MS Protein Standard (NP_009033), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a member of the guanylin family, and is expressed in the stomach and intestine. This protein functions as an endogenous ligand for the guanylate cyclase-C receptor and stimulates an increase in cyclic GMP, a key component of several intracellular signal transduction pathways. It maybe involved in salt and water secretion into the intestinal lumen as well as the renal tubules, and thus regulate electrolyte homeostasis in these tissues.

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