LNPEP Full-Length MS Protein Standard


Product Description:

Name LNPEP Full-Length MS Protein Standard
Cat# CPFL320692
Protein Nameleucyl/cystinyl aminopeptidase
SymbolLNPEP
SynonymsCAP; IRAP; P-LAP; PLAP
AccessionNM_005575
Cytogenetic5q15
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW117.2 kDa
Expression TrueORF CloneRC220692
DescriptionLNPEP Full-Length MS Protein Standard (NP_005566), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a zinc-dependent aminopeptidase that cleaves vasopressin, oxytocin, lys-bradykinin, met-enkephalin, dynorphin A and other peptide hormones. The protein can be secreted in maternal serum, reside in intracellular vesicles with the insulin-responsive glucose transporter GLUT4, or form a type II integral membrane glycoprotein. The protein catalyzes the final step in the conversion of angiotensinogen to angiotensin IV (AT4) and is also a receptor for AT4. Alternative splicing results in multiple transcript variants encoding different isoforms.

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