Product Description:

Name	CASK Full-Length MS Protein Standard
Cat#	CPFL320531
Protein Name	calcium/calmodulin-dependent serine protein kinase (MAGUK family)
Symbol	CASK
Synonyms	CAGH39; CAMGUK; CMG; FGS4; LIN2; MICPCH; MRXSNA; TNRC8
Accession	NM_003688
Cytogenetic	Xp11.4
Amino Acid Labeled	[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression Host	Human HEK293 cells
Predicted MW	104.3 kDa
Expression TrueORF Clone	RC220531
Description	CASK Full-Length MS Protein Standard (NP_003679), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a calcium/calmodulin-dependent serine protein kinase. The encoded protein is a MAGUK (membrane-associated guanylate kinase) protein family member. These proteins are scaffold proteins and the encoded protein is located at synapses in the brain. Mutations in this gene are associated with FG syndrome 4, mental retardation and microcephaly with pontine and cerebellar hypoplasia, and a form of X-linked mental retardation. Multiple transcript variants encoding different isoforms have been found for this gene.

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