JAK2 Full-Length MS Protein Standard


Product Description:

Name JAK2 Full-Length MS Protein Standard
Cat# CPFL320503
Protein NameJAK2 Janus kinase 2
SymbolJAK2
SynonymsJTK10; THCYT3
AccessionNM_004972
Cytogenetic9p24
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW130.5 kDa
Expression TrueORF CloneRC220503
DescriptionJAK2 Full-Length MS Protein Standard (NP_004963), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.

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