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MRPL30 Full-Length MS Protein Standard

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Product Description


NameMRPL30 Full-Length MS Protein Standard
Cat#CPFL320428
Protein Namemitochondrial ribosomal protein L30
SymbolMRPL30
SynonymsFLJ44438; MGC24095; MGC3314; MRP-L28; MRPL28; RPML28; MGC24095; MGC3314; MRP-L28; MRPL28; RPML28; OTTHUMP00000161222; mitochondrial ribosomal protein L30
AccessionNM_145213
Cytogenetic2q11.2
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionMRPL30 Full-Length MS Protein Standard (NP_660214), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Alternative splicing results in multiple transcript variants. Pseudogenes corresponding to this gene are found on chromosomes 6p and 12p. Read-through transcription also exists between this gene and the neighboring upstream lipoyltransferase 1 (LIPT1) gene.

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