ETF1 Full-Length MS Protein Standard


Product Description:

Name ETF1 Full-Length MS Protein Standard
Cat# CPFL320387
Protein Nameeukaryotic translation termination factor 1
SymbolETF1
SynonymsD5S1995; ERF; ERF1; RF1; SUP45L1; TB3-1
AccessionNM_004730
Cytogenetic5q31.1
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW48.9 kDa
Expression TrueORF CloneRC220387
DescriptionETF1 Full-Length MS Protein Standard (NP_004721), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a class-1 polypeptide chain release factor. The encoded protein plays an essential role in directing termination of mRNA translation from the termination codons UAA, UAG and UGA. This protein is a component of the SURF complex which promotes degradation of prematurely terminated mRNAs via the mechanism of nonsense-mediated mRNA decay (NMD). Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 6, 7, and X.

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