ADAMTS13 Full-Length MS Protein Standard


Product Description:

Name ADAMTS13 Full-Length MS Protein Standard
Cat# CPFL320320
Protein NameADAM metallopeptidase with thrombospondin type 1 motif, 13
SymbolADAMTS13
SynonymsADAM-TS13; ADAMTS-13; C9orf8; vWF-CP; VWFCP
AccessionNM_139025
Cytogenetic9q34
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW149.9 kDa
Expression TrueORF CloneRC220320
DescriptionADAMTS13 Full-Length MS Protein Standard (NP_620594), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a member of a family of proteins containing several distinct regions, including a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. The enzyme encoded by this gene specifically cleaves von Willebrand Factor (vWF). Defects in this gene are associated with thrombotic thrombocytopenic purpura. Alternative splicing results in multiple transcript variants.

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