TMIE Full-Length MS Protein Standard


Product Description:

Name TMIE Full-Length MS Protein Standard
Cat# CPFL320050
Protein Nametransmembrane inner ear
SymbolTMIE
SynonymsDFNB6
AccessionNM_147196
Cytogenetic3p21
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW14.8 kDa
Expression TrueORF CloneRC220050
DescriptionTMIE Full-Length MS Protein Standard (NP_671729), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a transmembrane inner ear protein. Studies in mouse suggest that this gene is required for normal postnatal maturation of sensory hair cells in the cochlea, including correct development of stereocilia bundles. This gene is one of multiple genes responsible for recessive non-syndromic deafness (DFNB), also known as autosomal recessive nonsyndromic hearing loss (ARNSHL), the most common form of congenitally acquired inherited hearing impairment.

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