RAD54L Full-Length MS Protein Standard


Product Description:

Name RAD54L Full-Length MS Protein Standard
Cat# CPFL320046
Protein NameRAD54-like (S. cerevisiae)
SymbolRAD54L
SynonymshHR54; HR54; hRAD54; RAD54A
AccessionNM_003579
Cytogenetic1p32
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW84.2 kDa
Expression TrueORF CloneRC220046
DescriptionRAD54L Full-Length MS Protein Standard (NP_003570), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene belongs to the DEAD-like helicase superfamily, and shares similarity with Saccharomyces cerevisiae Rad54, a protein known to be involved in the homologous recombination and repair of DNA. This protein has been shown to play a role in homologous recombination related repair of DNA double-strand breaks. The binding of this protein to double-strand DNA induces a DNA topological change, which is thought to facilitate homologous DNA paring, and stimulate DNA recombination. Alternative splicing results in multiple transcript variants encoding the same protein.

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