CHMP3 Full-Length MS Protein Standard


Product Description:

Name CHMP3 Full-Length MS Protein Standard
Cat# CPFL320006
Protein Namecharged multivesicular body protein 3
SymbolCHMP3
SynonymsCGI-149; NEDF; VPS24
AccessionNM_016079
Cytogenetic2p11.2
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW24.9 kDa
Expression TrueORF CloneRC220006
DescriptionVPS24 Full-Length MS Protein Standard (NP_057163), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a protein that sorts transmembrane proteins into lysosomes/vacuoles via the multivesicular body (MVB) pathway. This protein, along with other soluble coiled-coil containing proteins, forms part of the ESCRT-III protein complex that binds to the endosomal membrane and recruits additional cofactors for protein sorting into the MVB. This protein may also co-immunoprecipitate with a member of the IFG-binding protein superfamily. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ring finger protein 103 (RNF103) gene.

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