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BFSP2 Full-Length MS Protein Standard

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Product Description


NameBFSP2 Full-Length MS Protein Standard
Cat#CPFL319996
Protein Namebeaded filament structural protein 2, phakinin
SymbolBFSP2
SynonymsCP47; CP49; CTRCT12; LIFL-L; PHAKOSIN
AccessionNM_003571
Cytogenetic3q22.1
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionBFSP2 Full-Length MS Protein Standard (NP_003562), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. More than 99% of the vertebrate ocular lens is comprised of terminally differentiated lens fiber cells. Two lens-specific intermediate filament-like proteins, the protein product of this gene (phakinin), and filensin, are expressed only after fiber cell differentiation has begun. Both proteins are found in a structurally unique cytoskeletal element that is referred to as the beaded filament (BF). Mutations in this gene have been associated with juvenile-onset, progressive cataracts and Dowling-Meara epidermolysis bullosa simplex.

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