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LASP1 Full-Length MS Protein Standard

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Product Description


NameLASP1 Full-Length MS Protein Standard
Cat#CPFL319975
Protein NameLIM and SH3 protein 1
SymbolLASP1
SynonymsLasp-1; MLN50
AccessionNM_006148
Cytogenetic17q11-q21.3
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionLASP1 Full-Length MS Protein Standard (NP_006139), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a member of a subfamily of LIM proteins, characterized by a LIM motif and a domain of Src homology region 3, and also a member of the nebulin family of actin-binding proteins. The encoded protein is a cAMP and cGMP dependent signaling protein and binds to the actin cytoskeleton at extensions of the cell membrane. The encoded protein has been linked to metastatic breast cancer, hematopoetic tumors such as B-cell lymphomas, and colorectal cancer.

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