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MBNL2 Full-Length MS Protein Standard

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Product Description


NameMBNL2 Full-Length MS Protein Standard
Cat#CPFL319730
Protein Namemuscleblind-like 2 (Drosophila)
SymbolMBNL2
SynonymsMBLL; MBLL39; PRO2032
AccessionNM_207304
Cytogenetic13q32.1
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionMBNL2 Full-Length MS Protein Standard (NP_997187), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene is a member of the muscleblind protein family which was initially described in Drosophila melanogaster. This gene encodes a C3H-type zinc finger protein that modulates alternative splicing of pre-mRNAs. Muscleblind proteins bind specifically to expanded dsCUG RNA but not to normal size CUG repeats and may thereby play a role in the pathophysiology of myotonic dystrophy. Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined.

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