Name | A2ML1 Full-Length MS Protein Standard |
Cat# | CPFL319615 |
Protein Name | alpha-2-macroglobulin-like 1 |
Symbol | A2ML1 |
Synonyms | CPAMD9 |
Accession | NM_144670 |
Cytogenetic | 12p13.31 |
Amino Acid Labeled | [U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys |
Chemical Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Expression Host | Human HEK293 cells |
Predicted MW | 161 kDa |
Expression TrueORF Clone | RC219615 |
Description | A2ML1 Full-Length MS Protein Standard (NP_653271), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a member of the alpha-macroglobulin superfamily. The encoded protein acts as an inhibitor for several proteases, and has been reported as the p170 antigen recognized by autoantibodies in the autoimmune disease paraneoplastic pemphigus (PNP; PMID: 20805888). Alternative splicing results in multiple transcript variants. |
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