UHRF2 Full-Length MS Protein Standard


Product Description:

Name UHRF2 Full-Length MS Protein Standard
Cat# CPFL319579
Protein Nameubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase
SymbolUHRF2
SynonymsNIRF; RNF107; URF2
AccessionNM_152896
Cytogenetic9p24.1
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW89.8 kDa
Expression TrueORF CloneRC219579
DescriptionUHRF2 Full-Length MS Protein Standard (NP_690856), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a nuclear protein which is involved in cell-cycle regulation. The encoded protein is a ubiquitin-ligase capable of ubiquinating PCNP (PEST-containing nuclear protein), and together they may play a role in tumorigenesis. The encoded protein contains an NIRF_N domain, a PHD finger, a set- and ring-associated (SRA) domain, and a RING finger domain and several of these domains have been shown to be essential for the regulation of cell proliferation. This protein may also have a role in intranuclear degradation of polyglutamine aggregates. Alternative splicing results in multiple transcript variants some of which are non-protein coding.

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