DGCR8 Full-Length MS Protein Standard


Product Description:

Name DGCR8 Full-Length MS Protein Standard
Cat# CPFL319451
Protein NameDGCR8 microprocessor complex subunit
SymbolDGCR8
SynonymsC22orf12; DGCRK6; Gy1; pasha
AccessionNM_022720
Cytogenetic22q11.2
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW85.9 kDa
Expression TrueORF CloneRC219451
DescriptionDGCR8 Full-Length MS Protein Standard (NP_073557), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double-stranded RNA binding protein that functions as the non-catalytic subunit of the microprocessor complex. This protein is required for binding the double-stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein, Drosha. Alternate splicing results in multiple transcript variants.

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