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BCAT1 Full-Length MS Protein Standard

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Product Description


NameBCAT1 Full-Length MS Protein Standard
Cat#CPFL319229
Protein Namebranched chain amino-acid transaminase 1, cytosolic
SymbolBCAT1
SynonymsBCATC; BCT1; ECA39; MECA39; PNAS121; PP18
AccessionNM_005504
Cytogenetic12p12.1
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionBCAT1 Full-Length MS Protein Standard (NP_005495), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes the cytosolic form of the enzyme branched-chain amino acid transaminase. This enzyme catalyzes the reversible transamination of branched-chain alpha-keto acids to branched-chain L-amino acids essential for cell growth. Two different clinical disorders have been attributed to a defect of branched-chain amino acid transamination: hypervalinemia and hyperleucine-isoleucinemia. As there is also a gene encoding a mitochondrial form of this enzyme, mutations in either gene may contribute to these disorders. Alternatively spliced transcript variants have been described.

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