ASZ1 Full-Length MS Protein Standard


Product Description:

Name ASZ1 Full-Length MS Protein Standard
Cat# CPFL319070
Protein Nameankyrin repeat, SAM and basic leucine zipper domain containing 1
SymbolASZ1
SynonymsALP1; ANKL1; C7orf7; CT1.19; GASZ; Orf3
AccessionNM_130768
Cytogenetic7q31.2
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW53.3 kDa
Expression TrueORF CloneRC219070
DescriptionASZ1 Full-Length MS Protein Standard (NP_570124), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.

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