ERCC6 Full-Length MS Protein Standard


Product Description:

Name ERCC6 Full-Length MS Protein Standard
Cat# CPFL319020
Protein Nameexcision repair cross-complementing rodent repair deficiency, complementation group 6
SymbolERCC6
SynonymsARMD5; CKN2; COFS; COFS1; CSB; RAD26; UVSS1
AccessionNM_000124
Cytogenetic10q11.23
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW168.2 kDa
Expression TrueORF CloneRC219020
DescriptionERCC6 Full-Length MS Protein Standard (NP_000115), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a DNA-binding protein that is important in transcription-coupled excision repair. The encoded protein has ATP-stimulated ATPase activity, interacts with several transcription and excision repair proteins, and may promote complex formation at DNA repair sites. Mutations in this gene are associated with Cockayne syndrome type B and cerebrooculofacioskeletal syndrome 1. Naturally-occurring readthrough transcription occurs between this gene and the adjacent PGBD3 gene (GeneID:267004), and results in a fusion protein that shares sequence with the product of each individual gene. The readthrough locus is represented by GeneID:101243544.

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