PDE5A Full-Length MS Protein Standard


Product Description:

Name PDE5A Full-Length MS Protein Standard
Cat# CPFL318974
Protein Namephosphodiesterase 5A, cGMP-specific
SymbolPDE5A
SynonymsCGB-PDE; CN5A; PDE5
AccessionNM_033430
Cytogenetic4q27
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW94.6 kDa
Expression TrueORF CloneRC218974
DescriptionPDE5A Full-Length MS Protein Standard (NP_236914), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms.

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