HERC6 Full-Length MS Protein Standard


Product Description:

Name HERC6 Full-Length MS Protein Standard
Cat# CPFL318907
Protein NameHECT and RLD domain containing E3 ubiquitin protein ligase family member 6
SymbolHERC6
SynonymsFLJ20637
AccessionNM_017912
Cytogenetic4q22.1
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW114.9 kDa
Expression TrueORF CloneRC218907
DescriptionHERC6 Full-Length MS Protein Standard (NP_060382), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. HERC6 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins (Hochrainer et al., 2005 )

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