CHMP2A Full-Length MS Protein Standard


Product Description:

Name CHMP2A Full-Length MS Protein Standard
Cat# CPFL318563
Protein Namecharged multivesicular body protein 2A
SymbolCHMP2A
SynonymsBC-2; BC2; CHMP2; VPS2; VPS2A
AccessionNM_198426
Cytogenetic19q
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW24.9 kDa
Expression TrueORF CloneRC218563
DescriptionCHMP2A Full-Length MS Protein Standard (NP_940818), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. CHMP2A belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 )

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