MAP2K1 Full-Length MS Protein Standard


Product Description:

Name MAP2K1 Full-Length MS Protein Standard
Cat# CPFL318460
Protein Namemitogen-activated protein kinase kinase 1
SymbolMAP2K1
SynonymsCFC3; MAPKK1; MEK1; MKK1; PRKMK1
AccessionNM_002755
Cytogenetic15q22.1-q22.33
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW43.3 kDa
Expression TrueORF CloneRC218460
DescriptionMAP2K1 Full-Length MS Protein Standard (NP_002746), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development.

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