VAV3 Full-Length MS Protein Standard


Product Description:

Name VAV3 Full-Length MS Protein Standard
Cat# CPFL318352
Protein Namevav 3 guanine nucleotide exchange factor
SymbolVAV3
SynonymsFLJ40431
AccessionNM_001079874
Cytogenetic1p13.3
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW32.4 kDa
Expression TrueORF CloneRC218352
DescriptionVAV3 Full-Length MS Protein Standard (NP_001073343), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

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