ABL2 Full-Length MS Protein Standard


Product Description:

Name ABL2 Full-Length MS Protein Standard
Cat# CPFL318110
Protein Namev-abl Abelson murine leukemia viral oncogene homolog 2
SymbolABL2
SynonymsABLL; ARG
AccessionNM_005158
Cytogenetic1q25.2
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW126.5 kDa
Expression TrueORF CloneRC218110
DescriptionABL2 Full-Length MS Protein Standard (NP_005149), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a member of the Abelson family of nonreceptor tyrosine protein kinases. The protein is highly similar to the c-abl oncogene 1 protein, including the tyrosine kinase, SH2 and SH3 domains, and it plays a role in cytoskeletal rearrangements through its C-terminal F-actin- and microtubule-binding sequences. This gene is expressed in both normal and tumor cells, and is involved in translocation with the ets variant 6 gene in leukemia. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.

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