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IL17A Full-Length MS Protein Standard

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Product Description


NameIL17A Full-Length MS Protein Standard
Cat#CPFL318057
Protein Nameinterleukin 17A
SymbolIL17A
SynonymsCTLA8; IL-17; IL-17A; IL17
AccessionNM_002190
Cytogenetic6p12
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionIL17A Full-Length MS Protein Standard (NP_002181), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.

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