JAK3 Full-Length MS Protein Standard


Product Description:

Name JAK3 Full-Length MS Protein Standard
Cat# CPFL317928
Protein NameJanus kinase 3
SymbolJAK3
SynonymsJAK-3; JAK3_HUMAN; JAKL; L-JAK; LJAK
AccessionNM_000215
Cytogenetic19p13.1
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW124.9 kDa
Expression TrueORF CloneRC217928
DescriptionJAK3 Full-Length MS Protein Standard (NP_000206), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).

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