| Name | AKT2 Full-Length MS Protein Standard |
|---|---|
| Cat# | CPFL317733 |
| Protein Name | v-akt murine thymoma viral oncogene homolog 2 |
| Symbol | AKT2 |
| Synonyms | HIHGHH; PKBB; PKBBETA; PRKBB; RAC-BETA |
| Accession | NM_001626 |
| Cytogenetic | 19q13.1-q13.2 |
| Amino Acid Labeled | [U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys |
| Chemical Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Expression Host | Human HEK293 cells |
| Predicted MW | 55.6 kDa |
| Expression TrueORF Clone | RC217733 |
| Description | AKT2 Full-Length MS Protein Standard (NP_001617), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins. |
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