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AKT2 Full-Length MS Protein Standard

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Product Description


NameAKT2 Full-Length MS Protein Standard
Cat#CPFL317733
Protein Namev-akt murine thymoma viral oncogene homolog 2
SymbolAKT2
SynonymsHIHGHH; PKBB; PKBBETA; PRKBB; RAC-BETA
AccessionNM_001626
Cytogenetic19q13.1-q13.2
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionAKT2 Full-Length MS Protein Standard (NP_001617), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins.

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