IRF8 Full-Length MS Protein Standard


Product Description:

Name IRF8 Full-Length MS Protein Standard
Cat# CPFL317646
Protein Nameinterferon regulatory factor 8
SymbolIRF8
SynonymsH-ICSBP; ICSBP; ICSBP1; IMD32A; IMD32B; IRF-8
AccessionNM_002163
Cytogenetic16q24.1
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW48.2 kDa
Expression TrueORF CloneRC217646
DescriptionIRF8 Full-Length MS Protein Standard (NP_002154), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. Interferon consensus sequence-binding protein (ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection.

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